STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (292 aa)    
Predicted Functional Partners:
ADO49984.1
Transcriptional regulator, XRE family; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: helix-turn-helix domain protein; KEGG: cro:ROD_49131 transcriptional regulator; SMART: helix-turn-helix domain protein.
  
 
 0.953
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.952
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.942
ADO48495.1
NAD(P) transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.
     
 0.931
cobB
PFAM: Silent information regulator protein Sir2; KEGG: kva:Kvar_3263 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.930
sthA
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.910
ADO48496.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.908
nudC
NAD(+) diphosphatase; KEGG: ssn:SSON_4169 NADH pyrophosphatase; PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily.
     
 0.903
ADO47205.1
MazG family protein; KEGG: kpu:KP1_4397 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.
     
 0.902
ADO47373.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.680
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
Server load: medium (72%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.