| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO46993.1 | nudJ | Entcl_0718 | Entcl_2660 | KEGG: kpn:KPN_03448 ADP-ribose pyrophosphatase NudF; PFAM: NUDIX hydrolase. | PFAM: NUDIX hydrolase; KEGG: enc:ECL_02500 NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.930 |
| ADO46993.1 | thiM | Entcl_0718 | Entcl_1595 | KEGG: kpn:KPN_03448 ADP-ribose pyrophosphatase NudF; PFAM: NUDIX hydrolase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.900 |
| ADO46993.1 | ubiX | Entcl_0718 | Entcl_1414 | KEGG: kpn:KPN_03448 ADP-ribose pyrophosphatase NudF; PFAM: NUDIX hydrolase. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.900 |
| ADO47857.1 | ADO47858.1 | Entcl_1596 | Entcl_1597 | TIGRFAM: phosphomethylpyrimidine kinase; KEGG: kpu:KP1_3768 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Transcriptional regulator, GntR family; KEGG: cko:CKO_00682 hypothetical protein; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH. | 0.722 |
| ADO47857.1 | ADO50403.1 | Entcl_1596 | Entcl_4170 | TIGRFAM: phosphomethylpyrimidine kinase; KEGG: kpu:KP1_3768 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | KEGG: enc:ECL_00250 thiamine biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | 0.710 |
| ADO47857.1 | thiC | Entcl_1596 | Entcl_4165 | TIGRFAM: phosphomethylpyrimidine kinase; KEGG: kpu:KP1_3768 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.992 |
| ADO47857.1 | thiE | Entcl_1596 | Entcl_4166 | TIGRFAM: phosphomethylpyrimidine kinase; KEGG: kpu:KP1_3768 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
| ADO47857.1 | thiG | Entcl_1596 | Entcl_4169 | TIGRFAM: phosphomethylpyrimidine kinase; KEGG: kpu:KP1_3768 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.929 |
| ADO47857.1 | thiM | Entcl_1596 | Entcl_1595 | TIGRFAM: phosphomethylpyrimidine kinase; KEGG: kpu:KP1_3768 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.998 |
| ADO47858.1 | ADO47857.1 | Entcl_1597 | Entcl_1596 | Transcriptional regulator, GntR family; KEGG: cko:CKO_00682 hypothetical protein; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH. | TIGRFAM: phosphomethylpyrimidine kinase; KEGG: kpu:KP1_3768 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.722 |
| ADO47858.1 | thiM | Entcl_1597 | Entcl_1595 | Transcriptional regulator, GntR family; KEGG: cko:CKO_00682 hypothetical protein; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.675 |
| ADO47862.1 | thiM | Entcl_1601 | Entcl_1595 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sdy:SDY_2270 fructose-bisphosphate aldolase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.599 |
| ADO50403.1 | ADO47857.1 | Entcl_4170 | Entcl_1596 | KEGG: enc:ECL_00250 thiamine biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | TIGRFAM: phosphomethylpyrimidine kinase; KEGG: kpu:KP1_3768 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.710 |
| ADO50403.1 | thiC | Entcl_4170 | Entcl_4165 | KEGG: enc:ECL_00250 thiamine biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.996 |
| ADO50403.1 | thiE | Entcl_4170 | Entcl_4166 | KEGG: enc:ECL_00250 thiamine biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.996 |
| ADO50403.1 | thiG | Entcl_4170 | Entcl_4169 | KEGG: enc:ECL_00250 thiamine biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
| ADO50403.1 | thiM | Entcl_4170 | Entcl_1595 | KEGG: enc:ECL_00250 thiamine biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.608 |
| nudJ | ADO46993.1 | Entcl_2660 | Entcl_0718 | PFAM: NUDIX hydrolase; KEGG: enc:ECL_02500 NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | KEGG: kpn:KPN_03448 ADP-ribose pyrophosphatase NudF; PFAM: NUDIX hydrolase. | 0.930 |
| nudJ | thiM | Entcl_2660 | Entcl_1595 | PFAM: NUDIX hydrolase; KEGG: enc:ECL_02500 NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.900 |
| nudJ | ubiX | Entcl_2660 | Entcl_1414 | PFAM: NUDIX hydrolase; KEGG: enc:ECL_02500 NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.900 |