Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mdtAManually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: ecv:APECO1_1164 multidrug efflux system subunit MdtA; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (459 aa)    
Predicted Functional Partners:
mdtB
PFAM: acriflavin resistance protein; KEGG: kva:Kvar_1536 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 
 0.999
mdtC
PFAM: acriflavin resistance protein; KEGG: kva:Kvar_1535 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
 
 
 0.998
ADO48802.1
PFAM: protein of unknown function Spy-related; KEGG: kva:Kvar_3088 protein of unknown function Spy-related protein.
   
  
 0.958
ADO48199.1
PFAM: protein of unknown function DUF533; KEGG: ent:Ent638_2417 hypothetical protein.
   
    0.941
ADO47565.1
KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.
 
 
 0.937
ADO48282.1
KEGG: reu:Reut_A3424 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 
0.922
macB
ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.920
mdtD
PFAM: major facilitator superfamily MFS_1; KEGG: kpu:KP1_3745 multidrug efflux system protein MdtE.
 
  
 0.894
ADO47875.1
KEGG: kva:Kvar_1532 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver.
  
  
 0.893
ADO48281.1
PFAM: acriflavin resistance protein; KEGG: har:HEAR1043 multidrug ABC transporter membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.885
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.