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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO47882.1DNA-3-methyladenine glycosylase II; PFAM: AlkA domain protein; HhH-GPD family protein; KEGG: cko:CKO_00710 3-methyl-adenine DNA glycosylase II; SMART: HhH-GPD family protein. (280 aa)    
Predicted Functional Partners:
ADO47765.1
Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain-containing protein; helix-turn-helix- domain containing protein AraC type; methylguanine DNA methyltransferase ribonuclease domain protein; KEGG: ecc:c2754 ADA regulatory protein; SMART: Helix-turn-helix, AraC domain.
 
  
 0.961
ADO48838.1
Manually curated; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; KEGG: efe:EFER_1316 exonuclease III; PFAM: Endonuclease/exonuclease/phosphatase.
  
 0.888
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.598
ADO47881.1
KEGG: ecy:ECSE_2343 putative chaperone.
       0.531
ADO48503.1
methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.531
mdtD
PFAM: major facilitator superfamily MFS_1; KEGG: kpu:KP1_3745 multidrug efflux system protein MdtE.
     
 0.485
mdtC
PFAM: acriflavin resistance protein; KEGG: kva:Kvar_1535 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
       0.478
mdtA
Manually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: ecv:APECO1_1164 multidrug efflux system subunit MdtA; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.478
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
 
 0.477
ADO47875.1
KEGG: kva:Kvar_1532 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver.
       0.476
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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