STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ycgRYcgR family protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility. (243 aa)    
Predicted Functional Partners:
ADO48969.1
Anti-sigma-28 factor, FlgM; KEGG: cro:ROD_11381 negative regulator of flagellin synthesis (anti-sigma factor); TIGRFAM: Anti-sigma-28 factor FlgM family protein; PFAM: Anti-sigma-28 factor FlgM family protein.
 
  
 0.880
ADO48072.1
KEGG: ecg:E2348C_2043 flagellar protein FliS; TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS.
 
  
 0.863
ADO48970.1
PFAM: FlgN family protein; KEGG: set:SEN1877 flagella synthesis protein FlgN.
 
  
 0.849
ADO48073.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.841
ADO47715.1
KEGG: cko:CKO_00521 hypothetical protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver.
 
  
 0.822
ADO48171.1
PFAM: flagellar FlhE family protein; KEGG: set:SEN1091 flagellar protein FlhE precursor.
  
  
 0.753
ADO50372.1
KEGG: cro:ROD_37231 putative lipoprotein.
  
     0.750
ADO48160.1
PFAM: OmpA/MotB domain protein; KEGG: ses:SARI_01018 flagellar motor protein MotB.
 
 
 0.736
ADO48159.1
KEGG: sed:SeD_A1321 flagellar motor protein MotA.
 
 
 0.727
ADO50371.1
PFAM: protein of unknown function DUF1017; KEGG: ecx:EcHS_A4267 hypothetical protein.
  
     0.727
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.