Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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purRTranscriptional regulator, LacI family; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. (341 aa)    
Predicted Functional Partners:
ADO47446.1
KEGG: ent:Ent638_3055 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Peptidase S26, conserved region; Belongs to the peptidase S26 family.
   
    0.691
rimO
MiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
   
    0.601
ADO46763.1
KEGG: kpu:KP1_4936 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein.
    
 
 0.553
rplY
Ribosomal protein L25-like protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.
   
    0.510
glnS
KEGG: enc:ECL_03035 glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain.
   
   0.505
rne
Ribonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
   
   0.502
ADO50525.1
Phosphoenolpyruvate-protein phosphotransferase; KEGG: efe:EFER_3815 fused putative PTS enzymes: HPr component; enzyme I component; enzyme IIA component; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; phosphoryl transfer system HPr; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
   
 
 0.463
trpR
Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
   
  
 0.455
ADO47311.1
Regulatory protein MarR; KEGG: enc:ECL_04021 transcriptional repressor MprA; PFAM: regulatory protein MarR; SMART: regulatory protein MarR.
   
    0.448
ADO49700.1
TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; KEGG: kpe:KPK_0616 dihydroxyacetone kinase subunit M; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; PEP-utilising protein domain protein; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family.
   
 
 0.431
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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