| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO47153.1 | ADO47601.1 | Entcl_0881 | Entcl_1336 | PFAM: aldo/keto reductase; KEGG: kva:Kvar_0798 aldo/keto reductase. | KEGG: enc:ECL_03748 pyridoxal kinase; TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Belongs to the pyridoxine kinase family. | 0.915 |
| ADO47153.1 | pdxH | Entcl_0881 | Entcl_2192 | PFAM: aldo/keto reductase; KEGG: kva:Kvar_0798 aldo/keto reductase. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.906 |
| ADO47153.1 | pdxY | Entcl_0881 | Entcl_2194 | PFAM: aldo/keto reductase; KEGG: kva:Kvar_0798 aldo/keto reductase. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.912 |
| ADO47601.1 | ADO47153.1 | Entcl_1336 | Entcl_0881 | KEGG: enc:ECL_03748 pyridoxal kinase; TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Belongs to the pyridoxine kinase family. | PFAM: aldo/keto reductase; KEGG: kva:Kvar_0798 aldo/keto reductase. | 0.915 |
| ADO47601.1 | pdxH | Entcl_1336 | Entcl_2192 | KEGG: enc:ECL_03748 pyridoxal kinase; TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Belongs to the pyridoxine kinase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.919 |
| ADO47601.1 | pdxJ | Entcl_1336 | Entcl_1183 | KEGG: enc:ECL_03748 pyridoxal kinase; TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Belongs to the pyridoxine kinase family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.906 |
| ADO47601.1 | pdxY | Entcl_1336 | Entcl_2194 | KEGG: enc:ECL_03748 pyridoxal kinase; TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Belongs to the pyridoxine kinase family. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.924 |
| ADO48445.1 | anmK | Entcl_2191 | Entcl_2190 | PFAM: Protein of unknown function DUF2091, periplasmic; KEGG: kva:Kvar_2326 protein of unknown function DUF2091, periplasmic. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.586 |
| ADO48445.1 | pdxH | Entcl_2191 | Entcl_2192 | PFAM: Protein of unknown function DUF2091, periplasmic; KEGG: kva:Kvar_2326 protein of unknown function DUF2091, periplasmic. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.668 |
| ADO48445.1 | tyrS | Entcl_2191 | Entcl_2193 | PFAM: Protein of unknown function DUF2091, periplasmic; KEGG: kva:Kvar_2326 protein of unknown function DUF2091, periplasmic. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.439 |
| ADO49013.1 | gcvP | Entcl_2765 | Entcl_0849 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.825 |
| ADO49013.1 | pdxH | Entcl_2765 | Entcl_2192 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.555 |
| ADO49013.1 | pdxJ | Entcl_2765 | Entcl_1183 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.481 |
| anmK | ADO48445.1 | Entcl_2190 | Entcl_2191 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | PFAM: Protein of unknown function DUF2091, periplasmic; KEGG: kva:Kvar_2326 protein of unknown function DUF2091, periplasmic. | 0.586 |
| anmK | gcvP | Entcl_2190 | Entcl_0849 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.400 |
| anmK | pdxH | Entcl_2190 | Entcl_2192 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.486 |
| anmK | tyrS | Entcl_2190 | Entcl_2193 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.419 |
| carA | gcvP | Entcl_3685 | Entcl_0849 | KEGG: cko:CKO_03351 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.424 |
| carA | pdxH | Entcl_3685 | Entcl_2192 | KEGG: cko:CKO_03351 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.464 |
| gcvP | ADO49013.1 | Entcl_0849 | Entcl_2765 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.825 |