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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.
 
 0.984
ADO47570.1
PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: cko:CKO_00332 malic enzyme.
  
 
 0.970
ADO47948.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.965
ADO47984.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.965
ADO48467.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.965
ADO47947.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: kpe:KPK_1916 malate dehydrogenase.
  
 
 0.942
maeA
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: enc:ECL_01910 malate dehydrogenase.
  
 
 0.942
ADO50384.1
TIGRFAM: malate synthase A; KEGG: cko:CKO_03906 malate synthase; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
    
 0.934
mqo
TIGRFAM: malate/quinone oxidoreductase; KEGG: kva:Kvar_1424 malate/quinone oxidoreductase; PFAM: Malate:quinone-oxidoreductase.
    
 0.928
ADO47950.1
KEGG: kva:Kvar_2810 flavocytochrome c; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; NADH:flavin oxidoreductase/NADH oxidase; FMN-binding domain protein.
  
 0.911
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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