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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ADO48503.1methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (171 aa)    
Predicted Functional Partners:
ADO46473.1
TIGRFAM: DNA-3-methyladenine glycosylase I; KEGG: enc:ECL_00224 3-methyl-adenine DNA glycosylase I; PFAM: methyladenine glycosylase.
   
 0.742
ADO47882.1
DNA-3-methyladenine glycosylase II; PFAM: AlkA domain protein; HhH-GPD family protein; KEGG: cko:CKO_00710 3-methyl-adenine DNA glycosylase II; SMART: HhH-GPD family protein.
 
  
 0.595
ADO48501.1
PFAM: UspA domain-containing protein; KEGG: enc:ECL_02261 universal stress protein.
  
    0.558
ADO47765.1
Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain-containing protein; helix-turn-helix- domain containing protein AraC type; methylguanine DNA methyltransferase ribonuclease domain protein; KEGG: ecc:c2754 ADA regulatory protein; SMART: Helix-turn-helix, AraC domain.
 
  
0.552
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
   
 0.500
ADO48504.1
Smr protein/MutS2; KEGG: cko:CKO_01412 hypothetical protein; PFAM: Smr protein/MutS2; SMART: Smr protein/MutS2.
       0.493
ADO49145.1
AAA ATPase central domain protein; KEGG: kpu:KP1_1893 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.
 
   
 0.481
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
   
 0.470
ADO48502.1
Transcriptional regulator, Crp/Fnr family; KEGG: cro:ROD_16721 fumarate and nitrate reduction regulatory protein; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp.
       0.459
queG
Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.
      0.456
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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