Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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nikRTranscriptional regulator NikR, CopG family; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel. (133 aa)    
Predicted Functional Partners:
ADO47963.1
Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system.
  
 
 0.905
nikD
Nickel import ATP-binding protein NikD; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
 
   
 0.881
ADO48871.1
KEGG: ebr:ECB_03325 nickel transporter subunit; TIGRFAM: nickel ABC transporter, periplasmic nickel-binding protein; PFAM: extracellular solute-binding protein family 5.
     
 0.822
ADO48875.1
TIGRFAM: nickel import ATP-binding protein NikE; PFAM: ABC transporter related; KEGG: cko:CKO_04930 nickel transporter ATP-binding protein NikE; SMART: AAA ATPase.
 
   
 0.818
ADO48873.1
KEGG: cro:ROD_43191 nickel ABC transporter, permease protein; TIGRFAM: nickel ABC transporter, permease subunit NikC; PFAM: binding-protein-dependent transport systems inner membrane component.
  
  
 0.786
ADO48872.1
KEGG: eok:G2583_4198 nickel transport system permease protein NikB; TIGRFAM: nickel ABC transporter, permease subunit NikB; PFAM: binding-protein-dependent transport systems inner membrane component.
     
 0.779
birA
Bifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.612
znuC
ABC transporter related protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
     
 0.424
ADO48716.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: eca:ECA1228 hydrogenase 2 large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
   
 0.402
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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