| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO47423.1 | ADO48907.1 | Entcl_1156 | Entcl_2659 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | 0.405 |
| ADO47423.1 | der | Entcl_1156 | Entcl_1238 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.583 |
| ADO47423.1 | mnmA | Entcl_1156 | Entcl_2661 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. | 0.411 |
| ADO47423.1 | rlmL | Entcl_1156 | Entcl_2849 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.437 |
| ADO48838.1 | ADO48907.1 | Entcl_2588 | Entcl_2659 | Manually curated; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; KEGG: efe:EFER_1316 exonuclease III; PFAM: Endonuclease/exonuclease/phosphatase. | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | 0.661 |
| ADO48838.1 | rlmL | Entcl_2588 | Entcl_2849 | Manually curated; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; KEGG: efe:EFER_1316 exonuclease III; PFAM: Endonuclease/exonuclease/phosphatase. | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.547 |
| ADO48906.1 | ADO48907.1 | Entcl_2658 | Entcl_2659 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: kpu:KP1_2146 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | 0.580 |
| ADO48906.1 | ADO48911.1 | Entcl_2658 | Entcl_2663 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: kpu:KP1_2146 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | KEGG: cro:ROD_12211 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain-containing protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.884 |
| ADO48906.1 | hflD | Entcl_2658 | Entcl_2662 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: kpu:KP1_2146 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | PFAM: protein of unknown function DUF489; KEGG: cko:CKO_01839 hypothetical protein. | 0.441 |
| ADO48906.1 | mnmA | Entcl_2658 | Entcl_2661 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: kpu:KP1_2146 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. | 0.499 |
| ADO48906.1 | nudJ | Entcl_2658 | Entcl_2660 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: kpu:KP1_2146 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | PFAM: NUDIX hydrolase; KEGG: enc:ECL_02500 NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.559 |
| ADO48907.1 | ADO47423.1 | Entcl_2659 | Entcl_1156 | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.405 |
| ADO48907.1 | ADO48838.1 | Entcl_2659 | Entcl_2588 | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | Manually curated; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; KEGG: efe:EFER_1316 exonuclease III; PFAM: Endonuclease/exonuclease/phosphatase. | 0.661 |
| ADO48907.1 | ADO48906.1 | Entcl_2659 | Entcl_2658 | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: kpu:KP1_2146 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.580 |
| ADO48907.1 | ADO48911.1 | Entcl_2659 | Entcl_2663 | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | KEGG: cro:ROD_12211 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain-containing protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.570 |
| ADO48907.1 | cmk | Entcl_2659 | Entcl_2875 | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | TIGRFAM: cytidylate kinase; KEGG: cko:CKO_02163 cytidylate kinase; PFAM: cytidylate kinase region. | 0.625 |
| ADO48907.1 | der | Entcl_2659 | Entcl_1238 | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.690 |
| ADO48907.1 | hflD | Entcl_2659 | Entcl_2662 | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | PFAM: protein of unknown function DUF489; KEGG: cko:CKO_01839 hypothetical protein. | 0.570 |
| ADO48907.1 | mnmA | Entcl_2659 | Entcl_2661 | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. | 0.689 |
| ADO48907.1 | nudJ | Entcl_2659 | Entcl_2660 | PFAM: pseudouridine synthase; KEGG: enc:ECL_02499 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | PFAM: NUDIX hydrolase; KEGG: enc:ECL_02500 NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.791 |