Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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nagZGlycoside hydrolase family 3 domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (343 aa)    
Predicted Functional Partners:
yfeW
PFAM: beta-lactamase; KEGG: stt:t0381 hypothetical protein; Belongs to the peptidase S12 family. YfeW subfamily.
  
 0.935
ADO50147.1
KEGG: enc:ECL_00661 beta-N-acetylhexosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; Beta-N-acetylhexosaminidase, subunit a/b.
    
 0.930
ADO49173.1
Glycoside hydrolase family 18; KEGG: cko:CKO_02217 hypothetical protein; PFAM: glycoside hydrolase family 18; Chitinase A domain protein; PKD domain containing protein; Carbohydrate-binding family V/XII; SMART: chitinase II; PKD domain containing protein; Carbohydrate-binding family V/XII.
   
 
 0.905
anmK
Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
  
 0.893
thiK
Thiamine kinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate.
  
    0.817
lpoB
Membrane lipoprotein lipid attachment site; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.
  
    0.816
ADO48938.1
PFAM: protein of unknown function DUF1425; KEGG: ent:Ent638_1619 hypothetical protein.
     
 0.810
ADO48939.1
PFAM: histidine triad (HIT) protein; KEGG: kpu:KP1_2092 hypothetical protein.
     
 0.799
ADO48934.1
PFAM: protein of unknown function UPF0227; KEGG: ent:Ent638_1623 hypothetical protein; Belongs to the UPF0227 family.
  
  
 0.728
mpl
UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
 
   
 0.682
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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