| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO46719.1 | ADO46992.1 | Entcl_0441 | Entcl_0717 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | 0.523 |
| ADO46719.1 | ADO49159.1 | Entcl_0441 | Entcl_2912 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.654 |
| ADO46719.1 | macB | Entcl_0441 | Entcl_2911 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.507 |
| ADO46992.1 | ADO46719.1 | Entcl_0717 | Entcl_0441 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.523 |
| ADO46992.1 | ADO47565.1 | Entcl_0717 | Entcl_1299 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.499 |
| ADO46992.1 | ADO49159.1 | Entcl_0717 | Entcl_2912 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.900 |
| ADO46992.1 | ADO49573.1 | Entcl_0717 | Entcl_3328 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | Manually curated; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: kva:Kvar_3938 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.950 |
| ADO46992.1 | ADO50288.1 | Entcl_0717 | Entcl_4055 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | KEGG: mdtF; multidrug resistance protein MdtF; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.524 |
| ADO46992.1 | macB | Entcl_0717 | Entcl_2911 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.852 |
| ADO47565.1 | ADO46992.1 | Entcl_1299 | Entcl_0717 | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | 0.499 |
| ADO47565.1 | ADO49159.1 | Entcl_1299 | Entcl_2912 | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.694 |
| ADO47565.1 | macB | Entcl_1299 | Entcl_2911 | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.508 |
| ADO48281.1 | ADO49159.1 | Entcl_2026 | Entcl_2912 | PFAM: acriflavin resistance protein; KEGG: har:HEAR1043 multidrug ABC transporter membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.514 |
| ADO48687.1 | ADO49159.1 | Entcl_2436 | Entcl_2912 | KEGG: ent:Ent638_2136 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein. | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.585 |
| ADO48687.1 | macB | Entcl_2436 | Entcl_2911 | KEGG: ent:Ent638_2136 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein. | ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.504 |
| ADO49159.1 | ADO46719.1 | Entcl_2912 | Entcl_0441 | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.654 |
| ADO49159.1 | ADO46992.1 | Entcl_2912 | Entcl_0717 | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | 0.900 |
| ADO49159.1 | ADO47565.1 | Entcl_2912 | Entcl_1299 | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.694 |
| ADO49159.1 | ADO48281.1 | Entcl_2912 | Entcl_2026 | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | PFAM: acriflavin resistance protein; KEGG: har:HEAR1043 multidrug ABC transporter membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.514 |
| ADO49159.1 | ADO48687.1 | Entcl_2912 | Entcl_2436 | KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: ent:Ent638_2136 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein. | 0.585 |