Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO49166.1PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; KEGG: cko:CKO_02209 pyruvate dehydrogenase; Belongs to the TPP enzyme family. (572 aa)    
Predicted Functional Partners:
ADO48687.1
KEGG: ent:Ent638_2136 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein.
  
 
 0.971
ADO49888.1
TIGRFAM: acetolactate synthase, small subunit; KEGG: kva:Kvar_4299 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.
 
 0.960
ADO46308.1
PFAM: amino acid-binding ACT domain protein; KEGG: enc:ECL_00035 acetolactate synthase 1 regulatory subunit.
  
 0.943
ADO47570.1
PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: cko:CKO_00332 malic enzyme.
  
 0.937
lldD
FMN-dependent alpha-hydroxy acid dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
 
 0.928
ADO47947.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: kpe:KPK_1916 malate dehydrogenase.
  
 0.921
maeA
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: enc:ECL_01910 malate dehydrogenase.
  
 0.921
dld
D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
  
 0.911
ADO48192.1
TIGRFAM: pyruvate kinase; KEGG: efe:EFER_1218 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.911
ADO48381.1
TIGRFAM: pyruvate kinase; KEGG: cko:CKO_01709 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.911
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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