Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADO49212.1Nitroreductase; KEGG: ent:Ent638_1365 nitroreductase A; manually curated; PFAM: nitroreductase; Belongs to the flavin oxidoreductase frp family. (240 aa)    
Predicted Functional Partners:
ADO49471.1
KEGG: cko:CKO_02596 dihydropteridine reductase; PFAM: nitroreductase.
     
 0.952
ADO49213.1
PFAM: protein of unknown function DUF1418; KEGG: stt:t2023 hypothetical protein.
  
  
 0.933
ADO48433.1
PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: ssn:SSON_1506 N-ethylmaleimide reductase.
  
 
 0.905
ADO49068.1
PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: plu:plu1526 hypothetical protein.
  
 
 0.905
rimK
Manually curated; TIGRFAM: alpha-L-glutamate ligase, RimK family; KEGG: cko:CKO_02255 hypothetical protein; PFAM: RimK domain protein ATP-grasp; Belongs to the RimK family.
  
  
 0.822
ADO49126.1
Protein of unknown function DUF181; KEGG: kpu:KP1_1904 hypothetical protein; manually curated; PFAM: protein of unknown function DUF181.
  
  
 0.608
ADO46763.1
KEGG: kpu:KP1_4936 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein.
     
 0.586
birA
Bifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.573
ADO49024.1
KEGG: kva:Kvar_4530 ABC transporter related protein; PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase.
  
  
 0.566
ADO49214.1
KEGG: kva:Kvar_3497 glutaredoxin, GrxA family; TIGRFAM: glutaredoxin, GrxA family; PFAM: glutaredoxin.
  
  
 0.540
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
Server load: low (16%) [HD]