Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acrZProtein of unknown function DUF2592; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. (49 aa)    
Predicted Functional Partners:
ADO46992.1
KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein.
    
 
 0.674
ADO49315.1
KEGG: cko:CKO_02374 DNA-binding transcriptional regulator ModE; TIGRFAM: molybdate transport repressor, ModE; PFAM: TOBE domain-containing protein; regulatory protein LysR.
       0.670
ADO49191.1
KEGG: enc:ECL_02806 putative lipoprotein.
    
   0.579
ADO49572.1
Manually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kva:Kvar_3937 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
    
 
 0.527
ADO46719.1
KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.
    
   0.468
ADO49573.1
Manually curated; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: kva:Kvar_3938 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.
    
   0.468
ADO50288.1
KEGG: mdtF; multidrug resistance protein MdtF; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.
    
   0.468
ADO49316.1
ABC transporter related protein; KEGG: kpu:KP1_1718 putative molybdenum transport ATP-binding protein ModF; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.423
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
Server load: low (12%) [HD]