| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO48282.1 | ADO49495.1 | Entcl_2027 | Entcl_3249 | KEGG: reu:Reut_A3424 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.606 |
| ADO48282.1 | ADO49498.1 | Entcl_2027 | Entcl_3252 | KEGG: reu:Reut_A3424 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: kpn:KPN_pKPN3p05949 copper/silver efflux system outer membrane protein CusC; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.760 |
| ADO48282.1 | ADO49755.1 | Entcl_2027 | Entcl_3511 | KEGG: reu:Reut_A3424 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: shm:Shewmr7_2820 RND efflux system outer membrane lipoprotein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.795 |
| ADO48282.1 | mdtA | Entcl_2027 | Entcl_1620 | KEGG: reu:Reut_A3424 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Manually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: ecv:APECO1_1164 multidrug efflux system subunit MdtA; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.922 |
| ADO49323.1 | ADO49495.1 | Entcl_3077 | Entcl_3249 | KEGG: ent:Ent638_1243 zinc transporter ZitB; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein. | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.653 |
| ADO49323.1 | ADO49553.1 | Entcl_3077 | Entcl_3308 | KEGG: ent:Ent638_1243 zinc transporter ZitB; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein. | Copper-translocating P-type ATPase; KEGG: cko:CKO_02665 copper exporting ATPase; TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase. | 0.746 |
| ADO49495.1 | ADO48282.1 | Entcl_3249 | Entcl_2027 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | KEGG: reu:Reut_A3424 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.606 |
| ADO49495.1 | ADO49323.1 | Entcl_3249 | Entcl_3077 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | KEGG: ent:Ent638_1243 zinc transporter ZitB; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein. | 0.653 |
| ADO49495.1 | ADO49496.1 | Entcl_3249 | Entcl_3250 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kpn:KPN_pKPN3p05947 copper/silver efflux system membrane fusion protein CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.999 |
| ADO49495.1 | ADO49497.1 | Entcl_3249 | Entcl_3251 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | KEGG: enc:ECL_01961 Cu(I)/Ag(I) efflux system periplasmic protein CusF. | 0.971 |
| ADO49495.1 | ADO49498.1 | Entcl_3249 | Entcl_3252 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | KEGG: kpn:KPN_pKPN3p05949 copper/silver efflux system outer membrane protein CusC; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.885 |
| ADO49495.1 | ADO49499.1 | Entcl_3249 | Entcl_3253 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Two component heavy metal response transcriptional regulator, winged helix family; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; KEGG: cko:CKO_02615 DNA-binding transcriptional activator CusR; SMART: response regulator receiver. | 0.573 |
| ADO49495.1 | ADO49500.1 | Entcl_3249 | Entcl_3254 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. | 0.725 |
| ADO49495.1 | ADO49553.1 | Entcl_3249 | Entcl_3308 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Copper-translocating P-type ATPase; KEGG: cko:CKO_02665 copper exporting ATPase; TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase. | 0.712 |
| ADO49495.1 | ADO49755.1 | Entcl_3249 | Entcl_3511 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | KEGG: shm:Shewmr7_2820 RND efflux system outer membrane lipoprotein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.647 |
| ADO49495.1 | mdtA | Entcl_3249 | Entcl_1620 | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Manually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: ecv:APECO1_1164 multidrug efflux system subunit MdtA; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.596 |
| ADO49496.1 | ADO49495.1 | Entcl_3250 | Entcl_3249 | TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kpn:KPN_pKPN3p05947 copper/silver efflux system membrane fusion protein CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.999 |
| ADO49496.1 | ADO49497.1 | Entcl_3250 | Entcl_3251 | TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kpn:KPN_pKPN3p05947 copper/silver efflux system membrane fusion protein CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: enc:ECL_01961 Cu(I)/Ag(I) efflux system periplasmic protein CusF. | 0.990 |
| ADO49496.1 | ADO49498.1 | Entcl_3250 | Entcl_3252 | TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kpn:KPN_pKPN3p05947 copper/silver efflux system membrane fusion protein CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: kpn:KPN_pKPN3p05949 copper/silver efflux system outer membrane protein CusC; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.959 |
| ADO49496.1 | ADO49499.1 | Entcl_3250 | Entcl_3253 | TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kpn:KPN_pKPN3p05947 copper/silver efflux system membrane fusion protein CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Two component heavy metal response transcriptional regulator, winged helix family; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; KEGG: cko:CKO_02615 DNA-binding transcriptional activator CusR; SMART: response regulator receiver. | 0.627 |