Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO49496.1TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kpn:KPN_pKPN3p05947 copper/silver efflux system membrane fusion protein CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (425 aa)    
Predicted Functional Partners:
ADO49495.1
KEGG: ecl:EcolC_3422 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.999
ADO49497.1
KEGG: enc:ECL_01961 Cu(I)/Ag(I) efflux system periplasmic protein CusF.
 
 
 0.990
ADO49498.1
KEGG: kpn:KPN_pKPN3p05949 copper/silver efflux system outer membrane protein CusC; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein.
 
 
 0.959
macB
ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.920
ADO49755.1
KEGG: shm:Shewmr7_2820 RND efflux system outer membrane lipoprotein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein.
  
 
 0.818
ADO49500.1
Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system.
 
  
 0.788
ADO49499.1
Two component heavy metal response transcriptional regulator, winged helix family; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; KEGG: cko:CKO_02615 DNA-binding transcriptional activator CusR; SMART: response regulator receiver.
 
  
 0.627
ADO48281.1
PFAM: acriflavin resistance protein; KEGG: har:HEAR1043 multidrug ABC transporter membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.595
mdtC
PFAM: acriflavin resistance protein; KEGG: kva:Kvar_1535 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
 
 
 0.588
mdtB
PFAM: acriflavin resistance protein; KEGG: kva:Kvar_1536 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 
 0.585
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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