| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO46719.1 | ADO46992.1 | Entcl_0441 | Entcl_0717 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | 0.523 |
| ADO46719.1 | ADO47825.1 | Entcl_0441 | Entcl_1564 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpn:KPN_02576 multidrug resistance outer membrane protein MdtQ; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.632 |
| ADO46719.1 | ADO49498.1 | Entcl_0441 | Entcl_3252 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpn:KPN_pKPN3p05949 copper/silver efflux system outer membrane protein CusC; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.897 |
| ADO46719.1 | ADO49572.1 | Entcl_0441 | Entcl_3327 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | Manually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kva:Kvar_3937 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.898 |
| ADO46719.1 | ADO49755.1 | Entcl_0441 | Entcl_3511 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: shm:Shewmr7_2820 RND efflux system outer membrane lipoprotein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.763 |
| ADO46719.1 | acrZ | Entcl_0441 | Entcl_3068 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | Protein of unknown function DUF2592; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. | 0.567 |
| ADO46719.1 | macB | Entcl_0441 | Entcl_2911 | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.507 |
| ADO46992.1 | ADO46719.1 | Entcl_0717 | Entcl_0441 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | KEGG: kva:Kvar_0426 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.523 |
| ADO46992.1 | ADO47565.1 | Entcl_0717 | Entcl_1299 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.499 |
| ADO46992.1 | ADO49572.1 | Entcl_0717 | Entcl_3327 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | Manually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kva:Kvar_3937 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.984 |
| ADO46992.1 | ADO49573.1 | Entcl_0717 | Entcl_3328 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | Manually curated; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: kva:Kvar_3938 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.950 |
| ADO46992.1 | ADO50288.1 | Entcl_0717 | Entcl_4055 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | KEGG: mdtF; multidrug resistance protein MdtF; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | 0.524 |
| ADO46992.1 | acrZ | Entcl_0717 | Entcl_3068 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | Protein of unknown function DUF2592; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. | 0.577 |
| ADO46992.1 | macB | Entcl_0717 | Entcl_2911 | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.852 |
| ADO47565.1 | ADO46992.1 | Entcl_1299 | Entcl_0717 | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. | 0.499 |
| ADO47565.1 | ADO47825.1 | Entcl_1299 | Entcl_1564 | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpn:KPN_02576 multidrug resistance outer membrane protein MdtQ; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.615 |
| ADO47565.1 | ADO49498.1 | Entcl_1299 | Entcl_3252 | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: kpn:KPN_pKPN3p05949 copper/silver efflux system outer membrane protein CusC; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.888 |
| ADO47565.1 | ADO49572.1 | Entcl_1299 | Entcl_3327 | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | Manually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kva:Kvar_3937 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.887 |
| ADO47565.1 | ADO49755.1 | Entcl_1299 | Entcl_3511 | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | KEGG: shm:Shewmr7_2820 RND efflux system outer membrane lipoprotein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein. | 0.750 |
| ADO47565.1 | macB | Entcl_1299 | Entcl_2911 | KEGG: kva:Kvar_1252 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein. | ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.508 |