| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO48687.1 | ADO49609.1 | Entcl_2436 | Entcl_3364 | KEGG: ent:Ent638_2136 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | 0.647 |
| ADO49608.1 | ADO49609.1 | Entcl_3363 | Entcl_3364 | TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: eum:ECUMN_0482 hypothetical protein. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | 0.612 |
| ADO49609.1 | ADO48687.1 | Entcl_3364 | Entcl_2436 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | KEGG: ent:Ent638_2136 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein. | 0.647 |
| ADO49609.1 | ADO49608.1 | Entcl_3364 | Entcl_3363 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: eum:ECUMN_0482 hypothetical protein. | 0.612 |
| ADO49609.1 | bamA | Entcl_3364 | Entcl_3560 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | 0.737 |
| ADO49609.1 | cpoB | Entcl_3364 | Entcl_3079 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.717 |
| ADO49609.1 | ftsN | Entcl_3364 | Entcl_4341 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.668 |
| ADO49609.1 | lolA | Entcl_3364 | Entcl_2898 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.614 |
| ADO49609.1 | lptD | Entcl_3364 | Entcl_3669 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.669 |
| ADO49609.1 | tig | Entcl_3364 | Entcl_3369 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.590 |
| ADO49609.1 | tolB | Entcl_3364 | Entcl_3081 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.658 |
| ADO49609.1 | tolR | Entcl_3364 | Entcl_3083 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.583 |
| bamA | ADO49609.1 | Entcl_3560 | Entcl_3364 | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | 0.737 |
| bamA | cpoB | Entcl_3560 | Entcl_3079 | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.606 |
| bamA | lolA | Entcl_3560 | Entcl_2898 | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.800 |
| bamA | lptD | Entcl_3560 | Entcl_3669 | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.889 |
| bamA | tig | Entcl_3560 | Entcl_3369 | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.422 |
| bamA | tolB | Entcl_3560 | Entcl_3081 | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.857 |
| bamA | tolR | Entcl_3560 | Entcl_3083 | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.725 |
| cpoB | ADO49609.1 | Entcl_3079 | Entcl_3364 | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: kva:Kvar_3978 PpiC-type peptidyl-prolyl cis-trans isomerase. | 0.717 |