ADO49826.1 protein (Enterobacter lignolyticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ADO49826.1

Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (843 aa)

Predicted Functional Partners:

ADO46616.1

0.945

ftsI-2

0.938

ftsN

0.935

ADO47497.1

0.914

lpoB

0.909

ftsI

0.876

mrdA-2

0.818

mrdA

0.801

mrdB

0.787

ftsW

0.755

Your Current Organism:

Enterobacter lignolyticus

NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADO46616.1	ADO47497.1	Entcl_0338	Entcl_1230	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	Penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; manually curated; KEGG: kpu:KP1_4101 penicillin-binding protein 1C; TIGRFAM: penicillin-binding protein 1C.	0.923
ADO46616.1	ADO49826.1	Entcl_0338	Entcl_3585	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.945
ADO46616.1	ftsI	Entcl_0338	Entcl_1970	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.	0.532
ADO46616.1	ftsI-2	Entcl_0338	Entcl_3642	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.	0.556
ADO46616.1	ftsW	Entcl_0338	Entcl_3637	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.	0.632
ADO46616.1	mrdA	Entcl_0338	Entcl_1916	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.592
ADO46616.1	mrdA-2	Entcl_0338	Entcl_3161	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.616
ADO46616.1	mrdB	Entcl_0338	Entcl_3162	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.	0.690
ADO47497.1	ADO46616.1	Entcl_1230	Entcl_0338	Penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; manually curated; KEGG: kpu:KP1_4101 penicillin-binding protein 1C; TIGRFAM: penicillin-binding protein 1C.	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	0.923
ADO47497.1	ADO49826.1	Entcl_1230	Entcl_3585	Penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; manually curated; KEGG: kpu:KP1_4101 penicillin-binding protein 1C; TIGRFAM: penicillin-binding protein 1C.	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.914
ADO49826.1	ADO46616.1	Entcl_3585	Entcl_0338	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	TIGRFAM: penicillin-binding protein, 1A family; KEGG: ent:Ent638_3809 peptidoglycan synthetase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.	0.945
ADO49826.1	ADO47497.1	Entcl_3585	Entcl_1230	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; manually curated; KEGG: kpu:KP1_4101 penicillin-binding protein 1C; TIGRFAM: penicillin-binding protein 1C.	0.914
ADO49826.1	ftsI	Entcl_3585	Entcl_1970	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.	0.876
ADO49826.1	ftsI-2	Entcl_3585	Entcl_3642	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.	0.938
ADO49826.1	ftsN	Entcl_3585	Entcl_4341	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.	0.935
ADO49826.1	ftsW	Entcl_3585	Entcl_3637	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.	0.755
ADO49826.1	lpoB	Entcl_3585	Entcl_2689	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Membrane lipoprotein lipid attachment site; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.	0.909
ADO49826.1	mrdA	Entcl_3585	Entcl_1916	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.801
ADO49826.1	mrdA-2	Entcl_3585	Entcl_3161	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.818
ADO49826.1	mrdB	Entcl_3585	Entcl_3162	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.	0.787

page 1 of 4

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About