| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO49994.1 | ADO49995.1 | Entcl_3754 | Entcl_3755 | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | PFAM: Patatin; KEGG: ses:SARI_03015 hypothetical protein. | 0.883 |
| ADO49994.1 | ADO49996.1 | Entcl_3754 | Entcl_3756 | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | PFAM: protein of unknown function DUF1328; KEGG: ctu:Ctu_05910 hypothetical protein. | 0.562 |
| ADO49994.1 | gmk | Entcl_3754 | Entcl_0101 | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.431 |
| ADO49994.1 | lepA | Entcl_3754 | Entcl_1178 | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.417 |
| ADO49994.1 | lolD | Entcl_3754 | Entcl_2675 | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.436 |
| ADO49994.1 | metG | Entcl_3754 | Entcl_1580 | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.467 |
| ADO49994.1 | tsaD | Entcl_3754 | Entcl_0699 | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.460 |
| ADO49995.1 | ADO49994.1 | Entcl_3755 | Entcl_3754 | PFAM: Patatin; KEGG: ses:SARI_03015 hypothetical protein. | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | 0.883 |
| ADO49995.1 | ADO49996.1 | Entcl_3755 | Entcl_3756 | PFAM: Patatin; KEGG: ses:SARI_03015 hypothetical protein. | PFAM: protein of unknown function DUF1328; KEGG: ctu:Ctu_05910 hypothetical protein. | 0.626 |
| ADO49996.1 | ADO49994.1 | Entcl_3756 | Entcl_3754 | PFAM: protein of unknown function DUF1328; KEGG: ctu:Ctu_05910 hypothetical protein. | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | 0.562 |
| ADO49996.1 | ADO49995.1 | Entcl_3756 | Entcl_3755 | PFAM: protein of unknown function DUF1328; KEGG: ctu:Ctu_05910 hypothetical protein. | PFAM: Patatin; KEGG: ses:SARI_03015 hypothetical protein. | 0.626 |
| gmk | ADO49994.1 | Entcl_0101 | Entcl_3754 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | 0.431 |
| gmk | lepA | Entcl_0101 | Entcl_1178 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.677 |
| gmk | metG | Entcl_0101 | Entcl_1580 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.648 |
| lepA | ADO49994.1 | Entcl_1178 | Entcl_3754 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | 0.417 |
| lepA | gmk | Entcl_1178 | Entcl_0101 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.677 |
| lepA | metG | Entcl_1178 | Entcl_1580 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.487 |
| lepA | tsaD | Entcl_1178 | Entcl_0699 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.660 |
| lolD | ADO49994.1 | Entcl_2675 | Entcl_3754 | Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | PFAM: TatD-related deoxyribonuclease; KEGG: kpn:KPN_04835 putative hydrolase. | 0.436 |
| lolD | metG | Entcl_2675 | Entcl_1580 | Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.503 |