STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO49998.1KEGG: kpu:KP1_0788 nucleotidase; TIGRFAM: HAD superfamily (subfamily IA) hydrolase, TIGR02254; HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase. (226 aa)    
Predicted Functional Partners:
ADO47699.1
Metal dependent phosphohydrolase; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.
     
 0.946
surE
Stationary-phase survival protein SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
    
 0.943
ADO49556.1
PFAM: 5'-Nucleotidase domain-containing protein; metallophosphoesterase; KEGG: enc:ECL_01250 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family.
  
 
 0.938
ADO50188.1
KEGG: ent:Ent638_0392 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; TIGRFAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; PFAM: 5'-Nucleotidase domain-containing protein; metallophosphoesterase; Belongs to the 5'-nucleotidase family.
   
 
 0.935
udk
TIGRFAM: uridine kinase; KEGG: ctu:Ctu_27630 uridine kinase.
 
 
 0.927
ADO49386.1
KEGG: ent:Ent638_1190 UMP phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase.
  
 
 0.921
tdk
Thymidine kinase; Manually curated; KEGG: kpu:KP1_3312 thymidine kinase; PFAM: thymidine kinase.
    
 0.916
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
     
 0.911
ADO50438.1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
     
 0.906
ADO50485.1
PFAM: purine or other phosphorylase family 1; KEGG: ses:SARI_03742 hypothetical protein.
     
 0.906
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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