Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO50281.1KEGG: cko:CKO_02067 chaperone-modulator protein CbpM. (99 aa)    
Predicted Functional Partners:
cbpA
Heat shock protein DnaJ domain protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.
 
 
 0.992
ADO46910.1
PFAM: Fimbrial protein domain-containing protein; KEGG: stm:STM0025 fimbrial subunit.
  
     0.553
ADO46555.1
PFAM: Protein of unknown function DUF2500; KEGG: kva:Kvar_0268 protein of unknown function DUF2500.
  
     0.529
ADO48581.1
PFAM: protein of unknown function DUF1161; KEGG: ent:Ent638_1926 hypothetical protein.
  
     0.527
ADO50279.1
KEGG: enc:ECL_00018 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
  
    0.524
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.518
ADO50214.1
PFAM: acyl-CoA dehydrogenase domain-containing protein; KEGG: enc:ECL_00580 isovaleryl CoA dehydrogenase.
   
    0.510
ADO49528.1
PFAM: Fimbrial protein domain-containing protein; KEGG: enc:ECL_01279 fimbrial protein.
  
     0.479
tdcC
Serine transporter; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
  
     0.471
ADO47154.1
PFAM: Spore germination protein; KEGG: cko:CKO_04225 hypothetical protein.
  
     0.424
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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