STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO50281.1KEGG: cko:CKO_02067 chaperone-modulator protein CbpM. (99 aa)    
Predicted Functional Partners:
cbpA
Heat shock protein DnaJ domain protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.
 
 
 0.993
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.760
ADO46765.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein.
   
 
 0.592
ADO46910.1
PFAM: Fimbrial protein domain-containing protein; KEGG: stm:STM0025 fimbrial subunit.
  
     0.553
ADO46555.1
PFAM: Protein of unknown function DUF2500; KEGG: kva:Kvar_0268 protein of unknown function DUF2500.
  
     0.529
ADO48581.1
PFAM: protein of unknown function DUF1161; KEGG: ent:Ent638_1926 hypothetical protein.
  
     0.527
ADO48828.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; KEGG: kpu:KP1_2376 hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver.
   
 
 0.523
ADO50279.1
KEGG: enc:ECL_00018 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
  
    0.523
ADO48687.1
KEGG: ent:Ent638_2136 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein.
   
 
 0.505
ADO47333.1
Hpt sensor hybrid histidine kinase; KEGG: cko:CKO_04368 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3.
   
 
 0.502
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.