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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO50383.1KEGG: cro:ROD_37421 isocitrate lyase; TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase. (434 aa)    
Predicted Functional Partners:
ADO50384.1
TIGRFAM: malate synthase A; KEGG: cko:CKO_03906 malate synthase; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
 
 0.999
aceK
(Isocitrate dehydrogenase (NADP(+))) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
 
  
 0.946
ADO49849.1
KEGG: enc:ECL_00918 aconitate hydratase 2; TIGRFAM: aconitate hydratase 2; PFAM: Aconitase B; aconitate hydratase domain-containing protein; Belongs to the aconitase/IPM isomerase family.
     
 0.916
ADO49742.1
KEGG: glycoxylate carboligase GclA; TIGRFAM: glyoxylate carboligase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; Belongs to the TPP enzyme family.
     
 0.914
ghrA
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
   
 
 0.913
ghrB
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
     
 0.908
ADO48196.1
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; KEGG: kva:Kvar_1744 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.
     
 0.906
ADO48761.1
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
     
  0.900
ADO49920.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: kpe:KPK_4701 D-isomer specific 2-hydroxyacid dehydrogenase family protein.
     
 0.817
ADO47570.1
PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: cko:CKO_00332 malic enzyme.
   
  
 0.698
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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