Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO50441.1Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eum:ECUMN_4354 DNA-binding transcriptional activator, homocysteine-binding. (317 aa)    
Predicted Functional Partners:
ADO50556.1
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: cko:CKO_03051 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.954
ADO49432.1
PFAM: aminotransferase class I and II; KEGG: kva:Kvar_3722 aminotransferase class I and II.
   
  
 0.943
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
 
  
 0.876
ADO46918.1
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: enc:ECL_02361 cystathionine gamma-lyase.
   
  
 0.766
ADO47343.1
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: ect:ECIAI39_2453 cystathionine gamma-synthase (CGS) (O-succinylhomoserine (thiol)-lyase).
   
  
 0.766
ADO50565.1
O-succinylhomoserine (thiol)-lyase; KEGG: cro:ROD_38041 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
   
  
 0.766
metAS
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
   
    0.702
hdfR
Transcriptional regulator, LysR family; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
   
 0.602
ADO50562.1
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cko:CKO_03052 hypothetical protein.
  
     0.590
ADO50026.1
Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: etr:ETAE_2781 transcriptional regulator.
  
     0.563
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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