Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO50466.1HemY protein; KEGG: sbc:SbBS512_E4261 putative protoheme IX biogenesis protein; TIGRFAM: HemY protein; PFAM: HemY domain protein. (398 aa)    
Predicted Functional Partners:
ADO50465.1
KEGG: cko:CKO_00145 putative uroporphyrinogen III C-methyltransferase; PFAM: protein of unknown function DUF513 hemX.
 
  
 0.985
ADO50464.1
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
   
 0.868
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.818
ADO50462.1
KEGG: enc:ECL_04985 adenylate cyclase; PFAM: adenylate cyclase class-I; Belongs to the adenylyl cyclase class-1 family.
 
     0.801
lolB
Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
 
     0.784
ADO49616.1
PFAM: Uncharacterized lipoprotein; KEGG: kpu:KP1_1264 hypothetical protein.
  
     0.704
wecF
4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.
  
     0.686
ADO48083.1
PFAM: Protein of unknown function DUF2594; KEGG: kva:Kvar_1694 protein of unknown function DUF2594.
  
     0.668
wzyE
WzyE family protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.
  
     0.661
ADO49403.1
TIGRFAM: DNA polymerase III, delta subunit; KEGG: ecz:ECS88_0682 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.
  
     0.660
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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