| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO46642.1 | ADO49827.1 | Entcl_0364 | Entcl_3586 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; helicase domain protein; KEGG: eum:ECUMN_0145 ATP-dependent RNA helicase HrpB; SMART: DEAD-like helicase; helicase domain protein. | 0.575 |
| ADO46642.1 | rhlB | Entcl_0364 | Entcl_4248 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.557 |
| ADO46642.1 | rplC | Entcl_0364 | Entcl_0394 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.553 |
| ADO46642.1 | rplD | Entcl_0364 | Entcl_0395 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel. | 0.565 |
| ADO49827.1 | ADO46642.1 | Entcl_3586 | Entcl_0364 | TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; helicase domain protein; KEGG: eum:ECUMN_0145 ATP-dependent RNA helicase HrpB; SMART: DEAD-like helicase; helicase domain protein. | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.575 |
| ADO49827.1 | rhlB | Entcl_3586 | Entcl_4248 | TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; helicase domain protein; KEGG: eum:ECUMN_0145 ATP-dependent RNA helicase HrpB; SMART: DEAD-like helicase; helicase domain protein. | DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.570 |
| ADO49827.1 | rplC | Entcl_3586 | Entcl_0394 | TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; helicase domain protein; KEGG: eum:ECUMN_0145 ATP-dependent RNA helicase HrpB; SMART: DEAD-like helicase; helicase domain protein. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.510 |
| ADO49827.1 | rplD | Entcl_3586 | Entcl_0395 | TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; helicase domain protein; KEGG: eum:ECUMN_0145 ATP-dependent RNA helicase HrpB; SMART: DEAD-like helicase; helicase domain protein. | Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel. | 0.529 |
| gppA | rhlB | Entcl_4249 | Entcl_4248 | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.850 |
| nnrE | pnp | Entcl_3991 | Entcl_0533 | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.434 |
| nnrE | rhlB | Entcl_3991 | Entcl_4248 | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.590 |
| nnrE | rnr | Entcl_3991 | Entcl_3979 | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | 0.539 |
| pnp | nnrE | Entcl_0533 | Entcl_3991 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.434 |
| pnp | rhlB | Entcl_0533 | Entcl_4248 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.973 |
| pnp | rho | Entcl_0533 | Entcl_4246 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.933 |
| pnp | rne | Entcl_0533 | Entcl_2708 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.971 |
| pnp | rnr | Entcl_0533 | Entcl_3979 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | 0.678 |
| pnp | rplC | Entcl_0533 | Entcl_0394 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.863 |
| pnp | rplD | Entcl_0533 | Entcl_0395 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel. | 0.874 |
| rhlB | ADO46642.1 | Entcl_4248 | Entcl_0364 | DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.557 |
