STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO50673.1PFAM: bifunctional deaminase-reductase domain protein; KEGG: pol:Bpro_0286 bifunctional deaminase-reductase-like. (186 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.566
ADO47347.1
PFAM: thymidylate synthase; KEGG: bxe:Bxe_A0214 thymidylate synthase.
  
  
 0.566
ADO50669.1
PFAM: periplasmic solute binding protein; KEGG: ent:Ent638_1111 periplasmic solute binding protein; Belongs to the bacterial solute-binding protein 9 family.
       0.558
ADO50670.1
KEGG: ent:Ent638_1112 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.558
ADO50671.1
PFAM: ABC-3 protein; KEGG: ent:Ent638_1113 ABC-3 protein.
       0.558
ADO50672.1
PFAM: ABC-3 protein; KEGG: ent:Ent638_1114 ABC-3 protein.
       0.558
birA
Bifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
  
 0.506
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
 
 0.501
ADO46462.1
KEGG: enc:ECL_00209 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
 
 0.431
ADO47420.1
Chorismate mutase; KEGG: sbc:SbBS512_E2986 bifunctional chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase, type II.
     
 0.412
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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