| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUW_0359 | mutY | CUW_0359 | CUW_0342 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.872 |
| CUW_0465 | mutY | CUW_0465 | CUW_0342 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.526 |
| CUW_1094 | dnaN | CUW_1094 | CUW_1814 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00533; match to protein family HMM PF00929. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.986 |
| CUW_1094 | mutL | CUW_1094 | CUW_2120 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00533; match to protein family HMM PF00929. | DNA mismatch repair protein, C-terminal domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.466 |
| CUW_1094 | mutY | CUW_1094 | CUW_0342 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00533; match to protein family HMM PF00929. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.551 |
| CUW_1094 | polA | CUW_1094 | CUW_1025 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00533; match to protein family HMM PF00929. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.724 |
| CUW_1094 | xth | CUW_1094 | CUW_0023 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00533; match to protein family HMM PF00929. | Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.565 |
| CUW_1829 | mutY | CUW_1829 | CUW_0342 | Uracil DNA glycosylase family protein; Identified by match to protein family HMM PF03167. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.703 |
| CUW_1829 | polA | CUW_1829 | CUW_1025 | Uracil DNA glycosylase family protein; Identified by match to protein family HMM PF03167. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.418 |
| CUW_1829 | xth | CUW_1829 | CUW_0023 | Uracil DNA glycosylase family protein; Identified by match to protein family HMM PF03167. | Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.402 |
| ThiT | mutY | CUW_0344 | CUW_0342 | Putative proton-coupled thiamine transporter YuaJ; Identified by match to protein family HMM PF09515; match to protein family HMM TIGR02357. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.491 |
| dnaN | CUW_1094 | CUW_1814 | CUW_1094 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00533; match to protein family HMM PF00929. | 0.986 |
| dnaN | mutL | CUW_1814 | CUW_2120 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein, C-terminal domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.969 |
| dnaN | mutY | CUW_1814 | CUW_0342 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.823 |
| dnaN | polA | CUW_1814 | CUW_1025 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.996 |
| dnaN | recX | CUW_1814 | CUW_1459 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.405 |
| dnaN | xth | CUW_1814 | CUW_0023 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.920 |
| mutL | CUW_1094 | CUW_2120 | CUW_1094 | DNA mismatch repair protein, C-terminal domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00533; match to protein family HMM PF00929. | 0.466 |
| mutL | dnaN | CUW_2120 | CUW_1814 | DNA mismatch repair protein, C-terminal domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.969 |
| mutL | mutY | CUW_2120 | CUW_0342 | DNA mismatch repair protein, C-terminal domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.533 |
