node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CUW_1568 | coaD | CUW_1568 | CUW_0609 | Hypothetical protein; Identified by glimmer; putative. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.553 |
CUW_1568 | coaE | CUW_1568 | CUW_1036 | Hypothetical protein; Identified by glimmer; putative. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.516 |
CUW_1568 | guaA | CUW_1568 | CUW_1663 | Hypothetical protein; Identified by glimmer; putative. | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.631 |
CUW_2613 | coaD | CUW_2613 | CUW_0609 | comEA protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.712 |
RsmD | coaD | CUW_0610 | CUW_0609 | RNA methyltransferase, RsmD family; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.972 |
cmk | coaD | CUW_1077 | CUW_0609 | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.476 |
cmk | guaA | CUW_1077 | CUW_1663 | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.413 |
cmk | ribF | CUW_1077 | CUW_0467 | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family. | 0.817 |
coaBC | coaD | CUW_1472 | CUW_0609 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.940 |
coaBC | coaE | CUW_1472 | CUW_1036 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.662 |
coaBC | coaX | CUW_1472 | CUW_1471 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.986 |
coaBC | ribF | CUW_1472 | CUW_0467 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family. | 0.452 |
coaD | CUW_1568 | CUW_0609 | CUW_1568 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Hypothetical protein; Identified by glimmer; putative. | 0.553 |
coaD | CUW_2613 | CUW_0609 | CUW_2613 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | comEA protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426. | 0.712 |
coaD | RsmD | CUW_0609 | CUW_0610 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | RNA methyltransferase, RsmD family; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095. | 0.972 |
coaD | cmk | CUW_0609 | CUW_1077 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.476 |
coaD | coaBC | CUW_0609 | CUW_1472 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.940 |
coaD | coaE | CUW_0609 | CUW_1036 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.942 |
coaD | coaX | CUW_0609 | CUW_1471 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.954 |
coaD | guaA | CUW_0609 | CUW_1663 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.654 |