Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsdMType I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM TIGR00497. (495 aa)    
Predicted Functional Partners:
CUW_2200
Type I restriction modification DNA specificity domain protein; Identified by match to protein family HMM PF01420.
 
 0.999
hsdR
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.980
CUW_2656
Conserved hypothetical protein.
  
  
 0.683
CUW_2203
Conserved hypothetical protein; Identified by match to protein family HMM PF01863.
 
     0.677
CUW_2202
Hypothetical protein; Identified by glimmer; putative.
  
    0.674
CUW_1152
Conserved hypothetical protein; Identified by match to protein family HMM PF01863.
 
     0.580
CUW_2598
Restriction endonuclease; Identified by match to protein family HMM PF04471.
  
  
 0.571
CUW_0361
DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851.
 
   
 0.554
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 
 0.540
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.522
Your Current Organism:
Turicibacter sanguinis
NCBI taxonomy Id: 702450
Other names: T. sanguinis PC909, Turicibacter sanguinis PC909, Turicibacter sanguinis str. PC909, Turicibacter sanguinis strain PC909, Turicibacter sp. PC909
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