STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J9JPG2_ACYPIProfilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (127 aa)    
Predicted Functional Partners:
ACYPI002963
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
  
  
 
0.901
J9K081_ACYPI
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.847
X1WIB3_ACYPI
Uncharacterized protein.
    
 0.819
J9JZI9_ACYPI
WH1 domain-containing protein.
   
 0.813
X1WIG7_ACYPI
Uncharacterized protein.
    
 0.799
Tsr
Putative cofilin/actin depolymerizing factor-like protein; Belongs to the actin-binding proteins ADF family.
   
 0.786
J9JNQ4_ACYPI
Uncharacterized protein; Belongs to the actin family.
   
 0.773
J9K2X7_ACYPI
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.747
J9JKY4_ACYPI
FH2 domain-containing protein.
    
 0.737
J9KDP3_ACYPI
Uncharacterized protein.
    
 0.737
Your Current Organism:
Acyrthosiphon pisum
NCBI taxonomy Id: 7029
Other names: A. pisum, Acyrthosiphum pisum, pea aphid
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