STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J9JQ41_ACYPIUncharacterized protein. (535 aa)    
Predicted Functional Partners:
J9JSK0_ACYPI
Uncharacterized protein.
   
 0.622
J9K821_ACYPI
Receptor protein-tyrosine kinase.
    
 0.583
J9JJZ3_ACYPI
Uncharacterized protein.
    
 0.576
ACYPI009973
ACYPI009973 protein.
    
 0.545
J9K0M0_ACYPI
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
    
 0.539
X1XNB7_ACYPI
VHS domain-containing protein.
    
 0.539
J9JZ33_ACYPI
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.514
J9K7A9_ACYPI
Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.498
J9JXS1_ACYPI
Uncharacterized protein.
   
  
 0.487
J9JXQ6_ACYPI
Ubiquitin-like domain-containing protein.
    
  0.468
Your Current Organism:
Acyrthosiphon pisum
NCBI taxonomy Id: 7029
Other names: A. pisum, Acyrthosiphum pisum, pea aphid
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