STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J9K9C0_ACYPICOesterase domain-containing protein. (663 aa)    
Predicted Functional Partners:
J9KAA4_ACYPI
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
  
  
 
0.908
X1WIZ7_ACYPI
GP-PDE domain-containing protein.
     
 0.905
J9KAU3_ACYPI
Uncharacterized protein.
     
 0.900
ACYPI006090
ACYPI006090 protein.
     
 0.525
J9JYU9_ACYPI
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.493
J9JZP7_ACYPI
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.493
J9JKZ7_ACYPI
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
      
 0.491
J9JVX3_ACYPI
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.475
J9KQS8_ACYPI
COesterase domain-containing protein.
  
  
 0.440
J9JWD4_ACYPI
Uncharacterized protein.
      
 0.416
Your Current Organism:
Acyrthosiphon pisum
NCBI taxonomy Id: 7029
Other names: A. pisum, Acyrthosiphum pisum, pea aphid
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