STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J9LAS5_ACYPIUncharacterized protein. (323 aa)    
Predicted Functional Partners:
J9K322_ACYPI
Uncharacterized protein.
    
 0.998
J9JX81_ACYPI
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 0.916
Rpa2
RPA_C domain-containing protein.
   
 0.847
ACYPI000245
ACYPI000245 protein.
   
 0.813
J9K6I0_ACYPI
DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.
  
 0.782
J9K2Q0_ACYPI
Uncharacterized protein.
    
 0.732
J9JSG2_ACYPI
DNA helicase; Belongs to the MCM family.
   
 0.731
J9K335_ACYPI
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.716
J9JK45_ACYPI
DUF1767 domain-containing protein.
    
 0.714
ACYPI003821
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.704
Your Current Organism:
Acyrthosiphon pisum
NCBI taxonomy Id: 7029
Other names: A. pisum, Acyrthosiphum pisum, pea aphid
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.