STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2A9NBL5Rtt106 domain-containing protein. (522 aa)    
Predicted Functional Partners:
A0A2A9NNS3
HIT-type domain-containing protein.
    
   0.792
A0A2A9NMI5
WD_REPEATS_REGION domain-containing protein.
    
 
 0.659
A0A2A9NIU4
Uncharacterized protein.
    
 
 0.609
A0A2A9NTM7
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 
 0.567
A0A2A9NK60
Hydrolase_4 domain-containing protein.
     
 0.551
A0A2A9NL47
WD_REPEATS_REGION domain-containing protein.
   
 
 0.551
A0A2A9NY15
AB hydrolase-1 domain-containing protein.
     
 0.551
A0A2A9NRS4
F-box domain-containing protein.
   
 
 0.498
A0A2A9NU06
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
    
 
 0.474
A0A2A9NS91
Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.
    
 
 0.452
Your Current Organism:
Amanita thiersii
NCBI taxonomy Id: 703135
Other names: A. thiersii Skay4041, Amanita thiersii Skay4041
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.