| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F897_00848 | F897_00987 | F897_00848 | F897_00987 | Nudix hydrolase domain-containing protein. | Uncharacterized protein; Belongs to the DEAD box helicase family. | 0.680 |
| F897_00848 | F897_02509 | F897_00848 | F897_02509 | Nudix hydrolase domain-containing protein. | Uncharacterized protein. | 0.680 |
| F897_00848 | cpdA | F897_00848 | F897_00847 | Nudix hydrolase domain-containing protein. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.909 |
| F897_00848 | dksA | F897_00848 | F897_00846 | Nudix hydrolase domain-containing protein. | RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.640 |
| F897_00848 | nnrD | F897_00848 | F897_02463 | Nudix hydrolase domain-containing protein. | ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.923 |
| F897_00848 | prs | F897_00848 | F897_02917 | Nudix hydrolase domain-containing protein. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.899 |
| F897_00848 | rhlB | F897_00848 | F897_01748 | Nudix hydrolase domain-containing protein. | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.680 |
| F897_00848 | rnr | F897_00848 | F897_01057 | Nudix hydrolase domain-containing protein. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.774 |
| F897_00848 | rph | F897_00848 | F897_00499 | Nudix hydrolase domain-containing protein. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.671 |
| F897_00848 | thiC | F897_00848 | F897_00849 | Nudix hydrolase domain-containing protein. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.759 |
| F897_00987 | F897_00848 | F897_00987 | F897_00848 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Nudix hydrolase domain-containing protein. | 0.680 |
| F897_00987 | nnrD | F897_00987 | F897_02463 | Uncharacterized protein; Belongs to the DEAD box helicase family. | ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.906 |
| F897_00987 | prs | F897_00987 | F897_02917 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.492 |
| F897_00987 | rhlB | F897_00987 | F897_01748 | Uncharacterized protein; Belongs to the DEAD box helicase family. | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.487 |
| F897_00987 | rnr | F897_00987 | F897_01057 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.411 |
| F897_00987 | rph | F897_00987 | F897_00499 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.694 |
| F897_02509 | F897_00848 | F897_02509 | F897_00848 | Uncharacterized protein. | Nudix hydrolase domain-containing protein. | 0.680 |
| F897_02509 | nnrD | F897_02509 | F897_02463 | Uncharacterized protein. | ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.906 |
| F897_02509 | rph | F897_02509 | F897_00499 | Uncharacterized protein. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.683 |
| cpdA | F897_00848 | F897_00847 | F897_00848 | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Nudix hydrolase domain-containing protein. | 0.909 |
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