close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F897_01448Adenine phosphoribosyltransferase. (180 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
 0.988
F897_01677
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.945
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 
 0.943
F897_02596
Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
   
 0.940
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase.
  
 0.935
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.921
F897_00550
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 0.919
F897_01818
Glutamine amidotransferase type-1 domain-containing protein.
  
 
 0.912
F897_00693
Bifunctional metallophosphatase/5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.907
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
   
 
 0.903
Your Current Organism:
Acinetobacter variabilis
NCBI taxonomy Id: 70346
Other names: A. variabilis, Acinetobacter genomosp. 15, Acinetobacter genomospecies 15, Acinetobacter sp. 15, Acinetobacter sp. NIPH 2171, Acinetobacter variabilis Krizova et al. 2015, CCM 8555, CCUG 26390, CIP 110486, strain NIPH 2171
Server load: low (28%) [HD]