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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
nadEGlutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (541 aa)    
Predicted Functional Partners:
F897_02772
Nicotinate-nicotinamide nucleotide adenylyltransferase.
 
  
 0.984
F897_01548
Nudix hydrolase domain-containing protein.
  
 
 0.945
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.944
cobB
NAD-dependent protein deacylase; Belongs to the sirtuin family. Class III subfamily.
    
 0.943
F897_01116
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.932
F897_01633
Uncharacterized protein.
    
 0.909
F897_01114
NAD(P)(+) transhydrogenase (AB-specific), alpha subunit.
     
 0.903
F897_01115
NAD(P) transhydrogenase subunit alpha.
     
 0.903
F897_00920
Glutamine amidotransferase type-2 domain-containing protein.
    
 0.873
F897_00497
Nicotinate-nucleotide diphosphorylase (Carboxylating); Belongs to the NadC/ModD family.
  
 
 0.812
Your Current Organism:
Acinetobacter variabilis
NCBI taxonomy Id: 70346
Other names: A. variabilis, Acinetobacter genomosp. 15, Acinetobacter genomospecies 15, Acinetobacter sp. 15, Acinetobacter sp. NIPH 2171, Acinetobacter variabilis Krizova et al. 2015, CCM 8555, CCUG 26390, CIP 110486, strain NIPH 2171
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