STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A090M2N8Helicase, C-terminal. (1243 aa)    
Predicted Functional Partners:
A0A090M310
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.817
A0A096P958
Like-Sm (LSM) domain.
   
 
 0.785
A0A090MDM6
Eukaryotic translation initiation factor 4E (EIF-4E), conserved site; Belongs to the eukaryotic initiation factor 4E family.
    
 
 0.757
Q00XV3_OSTTA
FACT complex subunit Spt16p/Cdc68p.
    
 
 0.738
Q01F02_OSTTA
DNA-directed RNA polymerase, 30-40kDa subunit,conserved site.
    
 0.731
A0A090M451
Serine/threonine-protein kinase.
    
 0.726
Q017E1_OSTTA
Helicase, C-terminal.
   
 0.715
A0A096P9M4
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.626
A0A096PBQ4
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.626
A0A090M2K6
Histone core.
    
 0.613
Your Current Organism:
Ostreococcus tauri
NCBI taxonomy Id: 70448
Other names: O. tauri
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.