STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0101481aa long hypothetical protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (481 aa)    
Predicted Functional Partners:
PH0056
230aa long hypothetical HESA protein; Similar to Swiss_Prot:P46048 percent identity: 44.037 in 223aa; Swiss_Prot:P18500 percent identity: 41.872 in 206aa; PIR:A49890 percent identity: 39.450 in 223aa.
  
 
 0.806
PH1822
205aa long hypothetical protein; Similar to PIR:F64304 percent identity: 55.367 in 188aa.
  
   
 0.700
PH1524
115aa long hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.684
PH1699
447aa long hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
   
 0.653
PH0126
241aa long hypothetical protein; Similar to PIR:B64313 percent identity: 39.819 in 225aa.
 
   
 0.582
PH1123
605aa long hypothetical protein; Similar to PIR:D64491 percent identity: 55.201 in 612aa; PIR:S28724 percent identity: 50.251 in 612aa. motif=ATP/GTP-binding site motif A (P-loop).
  
   
 0.576
PH0121
1434aa long hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
  
     0.569
PH0295
170aa long hypothetical protein; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
 
   
 0.565
PH0100
115aa long hypothetical protein.
       0.551
PH0189
373aa long hypothetical protein; Similar to PIR:F64434 percent identity:29.508 in 395aa. motif=tubulin-beta mRNA autoregulation signal.
  
     0.549
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.