STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0159162aa long hypothetical protein; Probable biotin transporter; Belongs to the BioY family. (162 aa)    
Predicted Functional Partners:
PH0131
249aa long hypothetical protein; Similar to PIR:S62813 percent identity:37.736 in 108aa.
 
 0.993
PH0132
260aa long hypothetical transport protein; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 
 0.972
PH1815
284aa long hypothetical cobalt transport ATP-binding protein; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 
 0.963
PH0147
235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase; Similar to Swiss_Prot:P42975 percent identity: 36.245 in 250aa; owl:BSU20445 percent identity: 36.245 in 250aa.
 
   
 0.928
PH0951
283aa long hypothetical 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     
 0.803
PH0160
177aa long hypothetical protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity).
       0.747
PH0369
350aa long hypothetical galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
      
 0.709
PH1284
149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain; Similar to PIR:D49094 percent identity: 43.548 in 127aa. motif=biotin-requiring enzymes attachment site.
 
   
 0.519
PH0161
242aa long hypothetical protein; Similar to PIR:A64454 percent identity: 54.587 in 224aa.
     
 0.513
PH0251
191aa long hypothetical protein.
      
 0.474
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.