node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PH0201 | PH0245 | gene:9377111 | gene:9377161 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 197aa long hypothetical proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.899 |
PH0201 | PH0451 | gene:9377111 | gene:9377382 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 122aa long hypothetical protein. | 0.938 |
PH0201 | PH0470 | gene:9377111 | gene:9377404 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 298aa long hypothetical membrane protein; Similar to PIR:C64403 percent identity: 55.080 in 187aa; owl:MTCY2778 percent identity: 48.684 in 229aa; owl:ECAE0001554 percent identity: 44.958 in 239aa. | 0.647 |
PH0201 | PH0929 | gene:9377111 | gene:9377883 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 0.695 |
PH0201 | PH1116 | gene:9377111 | gene:9378075 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 582aa long hypothetical protein; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. | 0.635 |
PH0201 | PH1402 | gene:9377111 | gene:9378378 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 207aa long hypothetical proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.899 |
PH0201 | PH1488 | gene:9377111 | gene:9378467 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 170aa long hypothetical protein. | 0.938 |
PH0201 | PH1511 | gene:9377111 | gene:9378493 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 266aa long hypothetical erythrocyte band7 integral membrane protein; Similar to Swiss_Prot:P27105 percent identity: 51.351 in 224aa; Swiss_Prot:P54116 percent identity: 49.145 in 236aa; owl:MMU17297 percent identity: 48.718 in 236aa; Belongs to the band 7/mec-2 family. | 0.647 |
PH0201 | PH1553 | gene:9377111 | gene:9378543 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 260aa long hypothetical proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.955 |
PH0201 | PHS037 | gene:9377111 | gene:9378277 | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 51aa long hypothetical 50S ribosomal protein L40; Similar to Swiss_Prot:P54058 percent identity: 71.111 in 45aa; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.923 |
PH0245 | PH0201 | gene:9377161 | gene:9377111 | 197aa long hypothetical proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 0.899 |
PH0245 | PH0451 | gene:9377161 | gene:9377382 | 197aa long hypothetical proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 122aa long hypothetical protein. | 0.638 |
PH0245 | PH1402 | gene:9377161 | gene:9378378 | 197aa long hypothetical proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 207aa long hypothetical proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.904 |
PH0245 | PH1488 | gene:9377161 | gene:9378467 | 197aa long hypothetical proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 170aa long hypothetical protein. | 0.638 |
PH0245 | PH1553 | gene:9377161 | gene:9378543 | 197aa long hypothetical proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 260aa long hypothetical proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.956 |
PH0245 | PHS037 | gene:9377161 | gene:9378277 | 197aa long hypothetical proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 51aa long hypothetical 50S ribosomal protein L40; Similar to Swiss_Prot:P54058 percent identity: 71.111 in 45aa; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.609 |
PH0451 | PH0201 | gene:9377382 | gene:9377111 | 122aa long hypothetical protein. | 399aa long hypothetical 26S protease regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding a [...] | 0.938 |
PH0451 | PH0245 | gene:9377382 | gene:9377161 | 122aa long hypothetical protein. | 197aa long hypothetical proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.638 |
PH0451 | PH1402 | gene:9377382 | gene:9378378 | 122aa long hypothetical protein. | 207aa long hypothetical proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.638 |
PH0451 | PH1553 | gene:9377382 | gene:9378543 | 122aa long hypothetical protein. | 260aa long hypothetical proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.638 |