STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0208324aa long hypothetical translation initiation factor eIF-2B delta; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO. (324 aa)    
Predicted Functional Partners:
PH0961
275aa long hypothetical translation initiation factor eIF-2 alpha chain; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
   
 0.969
PH1706
411aa long hypothetical translation initiation factor eIF-2 gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
   
 0.964
PH1598
503aa long hypothetical pyrimidine-nucleoside phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
    
 0.813
PH0209
131aa long hypothetical protein; Similar to PIR:H64385 percent identity: 40.476 in 127aa; Belongs to the UPF0146 family.
       0.773
PH0939
430aa long hypothetical ribulose 1,5-bisphosphate carboxylase large subunit; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
 
  
 0.771
PH0380
327aa long hypothetical glucose-1 phosphate transferase; Similar to owl:SVAVIMDE1 percent identity:30.325 in 285aa; owl:SAMTMDE percent identity:30.108 in 287aa. motif=lipocalin signature.
   
 0.629
PH1022
416aa long hypothetical sugar-phosphate nucleotydyl transferase; Similar to Swiss_Prot:P41940 percent identity: 33.429 in 363aa; owl:S76785 percent identity: 34.930 in 367aa; owl:D89128 percent identity: 31.792 in 361aa. motif=serine proteases, subtilase family, active sites.
   
 0.629
PH1697
361aa long hypothetical mannose-1-phosphate guanyltransferase; Similar to owl:S76785 percent identity: 38.068 in 364aa; owl:S75920 percent identity: 47.107 in 255aa; owl:MTCY713 percent identity: 32.344 in 348aa.
   
 0.629
PH1925
419aa long hypothetical glucose-1-phosphate thymidylyltransferase; Similar to PIR:D64437 percent identity: 45.813 in 418aa; PIR:S76366 percent identity: 35.866 in 337aa; owl:STMSVIDEOX2 percent identity: 31.563 in 329aa.
   
 0.629
PH0207
428aa long hypothetical protein; Similar to owl:SS56KBFR17 percent identity: 50.886 in 398aa; owl:AB001488117 percent identity: 31.622 in 379aa; owl:BSY0947627 percent identity: 34.135 in 210aa.
       0.526
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.