node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PH0300 | PH0302 | gene:9377217 | gene:9377219 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 380aa long hypothetical Na(+)/H(+) antiporter; Similar to owl:BMU17283 percent identity: 37.634 in 374aa; owl:LLUPP percent identity: 33.245 in 379aa; Swiss_Prot:P26235 percent identity: 32.880 in 368aa. | 0.580 |
PH0300 | PH0316 | gene:9377217 | gene:9377234 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 334aa long hypothetical phosphoribosylformylglycinamide cyclo-ligase; Similar to PIR:D64325 percent identity: 55.738 in 317aa; Swiss_Prot:P12043 percent identity: 42.679 in 335aa; Swiss_Prot:P43848 percent identity: 43.279 in 317aa. | 0.714 |
PH0300 | PH0962 | gene:9377217 | gene:9377917 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 407aa long hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 0.656 |
PH0300 | PH1242 | gene:9377217 | gene:9378204 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 262aa long hypothetical pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.443 |
PH0300 | PH1401 | gene:9377217 | gene:9378377 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 203aa long hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. | 0.762 |
PH0300 | PH1538 | gene:9377217 | gene:9378523 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 409aa long hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.481 |
PH0300 | PH1617 | gene:9377217 | gene:9378607 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 336aa long hypothetical UDP-N-acetylglucosamine 2-epimerase; Similar to PIR:G64487 percent identity: 57.143 in 132aa; owl:SAU8197315 percent identity: 43.925 in 107aa. | 0.457 |
PH0300 | PH1644 | gene:9377217 | gene:9378637 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 334aa long hypothetical centromere/microtubule binding protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.769 |
PH0300 | PH1858 | gene:9377217 | gene:9378863 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 253aa long hypothetical protein; Similar to PIR:F64316 percent identity: 47.059 in 269aa; owl:MTCY26113 percent identity: 36.145 in 254aa; owl:S72844 percent identity: 35.887 in 259aa. | 0.777 |
PH0300 | PH1867 | gene:9377217 | gene:9378873 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 617aa long hypothetical protein; Similar to PIR:G64441 percent identity: 54.442 in 577aa; owl:CEZK8632 percent identity: 45.265 in 581aa; owl:SPAC29A418 percent identity: 45.977 in 576aa. | 0.441 |
PH0302 | PH0300 | gene:9377219 | gene:9377217 | 380aa long hypothetical Na(+)/H(+) antiporter; Similar to owl:BMU17283 percent identity: 37.634 in 374aa; owl:LLUPP percent identity: 33.245 in 379aa; Swiss_Prot:P26235 percent identity: 32.880 in 368aa. | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 0.580 |
PH0316 | PH0300 | gene:9377234 | gene:9377217 | 334aa long hypothetical phosphoribosylformylglycinamide cyclo-ligase; Similar to PIR:D64325 percent identity: 55.738 in 317aa; Swiss_Prot:P12043 percent identity: 42.679 in 335aa; Swiss_Prot:P43848 percent identity: 43.279 in 317aa. | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 0.714 |
PH0962 | PH0300 | gene:9377917 | gene:9377217 | 407aa long hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 0.656 |
PH0962 | PH1242 | gene:9377917 | gene:9378204 | 407aa long hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 262aa long hypothetical pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.869 |
PH0962 | PH1401 | gene:9377917 | gene:9378377 | 407aa long hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 203aa long hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. | 0.927 |
PH0962 | PH1538 | gene:9377917 | gene:9378523 | 407aa long hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 409aa long hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.848 |
PH0962 | PH1644 | gene:9377917 | gene:9378637 | 407aa long hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 334aa long hypothetical centromere/microtubule binding protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.845 |
PH1242 | PH0300 | gene:9378204 | gene:9377217 | 262aa long hypothetical pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. | 0.443 |
PH1242 | PH0962 | gene:9378204 | gene:9377917 | 262aa long hypothetical pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 407aa long hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 0.869 |
PH1242 | PH1538 | gene:9378204 | gene:9378523 | 262aa long hypothetical pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 409aa long hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.896 |