STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0572445aa long hypothetical NADH oxidase; Acts as a coenzyme A disulfide reductase. Specific for CoA disulfide. Shows a slow NAD(P)H oxidase activity in the presence of high concentrations of substrate-level FAD. This demonstrates that it is not likely to act as an NADH oxidase in vivo. (445 aa)    
Predicted Functional Partners:
PH1353
679aa long hypothetical formate dehydrogenase; Similar to owl:MTU526812 percent identity: 48.550 in 677aa; Swiss_Prot:P06131 percent identity: 44.104 in 681aa; owl:MTU738071 percent identity: 43.381 in 646aa.
    
 0.908
PH1085
411aa long hypothetical flavoprotein; Similar to PIR:D64391 percent identity: 32.386 in 367aa; PIR:D64393 percent identity: 27.616 in 358aa; owl:ECAE000355 percent identity: 26.389 in 369aa.
    
 0.902
PH1364
382aa long hypothetical sarcosine oxidase; Similar to Swiss_Prot:P40875 percent identity: 29.752 in 377aa; owl:I40887 percent identity: 29.477 in 377aa.
  
 
 0.559
PH1751
377aa long hypothetical sarcosine oxidase; Similar to PIR:S16133 percent identity:37.104 in 227aa; PIR:I40887 percent identity:28.487 in 352aa.
  
 
 0.559
PH1359
639aa long hypothetical protein; Similar to Swiss_Prot:P37519 percent identity: 30.413 in 646aa.
    
 0.518
PH1757
236aa long hypothetical 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.470
PH0570
478aa long hypothetical pyruvate kinase; Similar to PIR:A57418 percent identity:76.037 in 217aa; PIR:S76677 percent identity:42.128 in 484aa; Swiss_Prot:Q02499 percent identity:43.991 in 475aa. motif=eukaryotic thiol (cysteine) proteases active sites; Belongs to the pyruvate kinase family.
  
  
 0.432
PH1483
102aa long hypothetical 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.418
PH0569
114aa long hypothetical protein.
       0.407
PH0642
262aa long hypothetical protein; Similar to owl:PBU4258077 percent identity:40.397 in 157aa; owl:HPAE0005494 percent identity:38.136 in 257aa; Swiss_Prot:P55176 percent identity:32.540 in 265aa. motif=ATP/GTP-binding site motif A (P-loop).
   
  
 0.406
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.