STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0624177aa long hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (177 aa)    
Predicted Functional Partners:
PH1909
179aa long hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
  
 0.987
PH0515
195aa long hypothetical protein; motif=ATP/GTP-binding site motif A (P-loop).
    
 0.917
PH1444
401aa long hypothetical protein DFP; Similar to PIR:A64414 percent identity: 42.159 in 405aa; Swiss_Prot:P44953 percent identity: 36.579 in 400aa; Swiss_Prot:P24285 percent identity: 33.509 in 403aa.
    
 0.912
PH0623
153aa long hypothetical protein.
       0.598
PH0625
440aa long hypothetical protein; Similar to PIR:F64373 percent identity: 44.111 in 447aa; owl:ECOK12RIII17 percent identity: 33.957 in 389aa; owl:ECAE00034410 percent identity: 33.957 in 389aa.
       0.598
PH0633
181aa long hypothetical ubiquinol-cytochrome c reductase complex subunit VI; Similar to PIR:G64367 percent identity: 54.717 in 159aa; owl:EGHUMSIM percent identity: 45.513 in 159aa; owl:AF013804 percent identity: 42.675 in 160aa; Belongs to the universal ribosomal protein uL16 family.
  
     0.514
PH0527
151aa long hypothetical protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity); Belongs to the prefoldin subunit alpha family.
  
     0.474
PH1940
109aa long hypothetical 50S ribosomal protein L44; Binds to the 23S rRNA.
  
     0.474
PH0052
227aa long hypothetical fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
    0.454
PH1987
324aa long hypothetical O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
 
     0.451
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.