Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PH0622 | PH0929 | gene:9377564 | gene:9377883 | 686aa long hypothetical DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand [...] | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 0.886 |
| PH0622 | PH0930 | gene:9377564 | gene:9377884 | 686aa long hypothetical DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand [...] | 413aa long hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.813 |
| PH0622 | PH1415 | gene:9377564 | gene:9378391 | 686aa long hypothetical DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand [...] | 343aa long hypothetical 5' nuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.724 |
| PH0622 | PH1893 | gene:9377564 | gene:9378900 | 686aa long hypothetical DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand [...] | 361aa long hypothetical protein; Similar to PIR:F64444 percent identity:33.486 in 240aa. | 0.914 |
| PH0622 | PH1947 | gene:9377564 | gene:9378960 | 686aa long hypothetical DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand [...] | 1235aa long hypothetical DNA-directed DNA polymerase; Similar to PIR:S68593 percent identity: 75.831 in 1312aa; Swiss_Prot:P30317 percent identity: 67.133 in 1082aa; owl:PYWKODPOL percent identity: 75.792 in 1671aa. motif=DNA polymerase family B signature; protein splicing signature; Belongs to the DNA polymerase type-B family. | 0.577 |
| PH0859 | PH0929 | gene:9377810 | gene:9377883 | 590aa long hypothetical transport protein; Similar to PIR:G64389 percent identity: 61.921 in 596aa; owl:S63672 percent identity: 48.048 in 594aa; PIR:S58091 percent identity: 50.000 in 599aa. motif=4Fe-4S ferredoxins, iron-sulfur binding region signature; ABC transporters family signature; ATP/. | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 0.769 |
| PH0928 | PH0929 | gene:9377882 | gene:9377883 | 442aa long hypothetical protein. | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 0.824 |
| PH0928 | PH0930 | gene:9377882 | gene:9377884 | 442aa long hypothetical protein. | 413aa long hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.789 |
| PH0928 | PH0932 | gene:9377882 | gene:9377886 | 442aa long hypothetical protein. | 555aa long hypothetical protein; Similar to PIR:D64478 percent identity: 41.295 in 463aa; PIR:H64510 percent identity: 35.743 in 533aa; PIR:D64495 percent identity: 39.378 in 436aa. motif=ATP/GTP-binding site motif A (P-loop); gram-positive cocci surface proteins 'anchoring' hexapeptide. | 0.936 |
| PH0928 | PH0934 | gene:9377882 | gene:9377888 | 442aa long hypothetical protein. | 390aa long hypothetical Na(+)/H(+) antiporter; Similar to Swiss_Prot:P26235 percent identity: 29.894 in 391aa; owl:BMU17283 percent identity: 29.630 in 391aa; owl:LLUPP percent identity: 26.133 in 389aa. | 0.654 |
| PH0929 | PH0622 | gene:9377883 | gene:9377564 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 686aa long hypothetical DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand [...] | 0.886 |
| PH0929 | PH0859 | gene:9377883 | gene:9377810 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 590aa long hypothetical transport protein; Similar to PIR:G64389 percent identity: 61.921 in 596aa; owl:S63672 percent identity: 48.048 in 594aa; PIR:S58091 percent identity: 50.000 in 599aa. motif=4Fe-4S ferredoxins, iron-sulfur binding region signature; ABC transporters family signature; ATP/. | 0.769 |
| PH0929 | PH0928 | gene:9377883 | gene:9377882 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 442aa long hypothetical protein. | 0.824 |
| PH0929 | PH0930 | gene:9377883 | gene:9377884 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 413aa long hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.999 |
| PH0929 | PH0932 | gene:9377883 | gene:9377886 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 555aa long hypothetical protein; Similar to PIR:D64478 percent identity: 41.295 in 463aa; PIR:H64510 percent identity: 35.743 in 533aa; PIR:D64495 percent identity: 39.378 in 436aa. motif=ATP/GTP-binding site motif A (P-loop); gram-positive cocci surface proteins 'anchoring' hexapeptide. | 0.914 |
| PH0929 | PH0934 | gene:9377883 | gene:9377888 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 390aa long hypothetical Na(+)/H(+) antiporter; Similar to Swiss_Prot:P26235 percent identity: 29.894 in 391aa; owl:BMU17283 percent identity: 29.630 in 391aa; owl:LLUPP percent identity: 26.133 in 389aa. | 0.714 |
| PH0929 | PH1415 | gene:9377883 | gene:9378391 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 343aa long hypothetical 5' nuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.904 |
| PH0929 | PH1622 | gene:9377883 | gene:9378612 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 559aa long hypothetical DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.754 |
| PH0929 | PH1893 | gene:9377883 | gene:9378900 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 361aa long hypothetical protein; Similar to PIR:F64444 percent identity:33.486 in 240aa. | 0.770 |
| PH0929 | PH1947 | gene:9377883 | gene:9378960 | 879aa long hypothetical purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 1235aa long hypothetical DNA-directed DNA polymerase; Similar to PIR:S68593 percent identity: 75.831 in 1312aa; Swiss_Prot:P30317 percent identity: 67.133 in 1082aa; owl:PYWKODPOL percent identity: 75.792 in 1671aa. motif=DNA polymerase family B signature; protein splicing signature; Belongs to the DNA polymerase type-B family. | 0.856 |
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