STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0949295aa long hypothetical MRP protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (295 aa)    
Predicted Functional Partners:
PH0950
268aa long hypothetical protein.
     
 0.777
PH1447
394aa long hypothetical NADH-ubiquinone oxidoreductase subunit; Similar to Swiss_Prot:P22142 percent identity: 36.639 in 387aa; PIR:S53862 percent identity: 36.088 in 387aa; owl:TAU529173 percent identity: 35.215 in 396aa. motif=respiratory-chain NADH dehydrogenase 49 Kd subunit signature; Belongs to the complex I 49 kDa subunit family.
     
 0.642
PH1448
174aa long hypothetical NADH-ubiquinone oxidoreductase subunit; Similar to Swiss_Prot:P23710 percent identity:33.628 in 119aa; Swiss_Prot:P34944 percent identity:32.743 in 119aa.
    
 0.642
PH1581
139aa long hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
   
 
 0.629
PH1449
195aa long hypothetical NADH-ubiquinone oxidoreductase subunit; Similar to Swiss_Prot:P52766 percent identity:48.485 in 133aa; Swiss_Prot:P06410 percent identity:45.926 in 136aa; Swiss_Prot:P06409 percent identity:48.485 in 133aa; Belongs to the complex I 20 kDa subunit family.
   
 
 0.584
PH0948
175aa long hypothetical protein.
       0.550
PH0947
249aa long hypothetical protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. Belongs to the sirtuin family. Class III subfamily.
  
    0.461
PH1875
432aa long hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
  
  
 0.455
PH0822
121aa long hypothetical protein; Similar to PIR:D64372 percent identity:35.106 in 97aa.
 
  
 0.412
PH1383
177aa long hypothetical protein.
 
  
 0.407
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.